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The Ultimate Slay the Spire Relic Tier List (Ranked From S to F)
New builds and patch cycles keep players hunting clear power rankings. This guide breaks down every relic so you can optimize runs without chasing trends.
The Ultimate Slay the Spire Relic Tier List (Ranked From S to F) is a ranked order of relics from strongest to weakest. Studies indicate these rankings reflect real combat impact across many runs and difficulty levels.
Why these tiers actually matter
Higher relics smooth runs; lower ones create risky bottlenecks. This list matches card synergy, upgrade value, and win rate together. Research shows consistent patterns emerge when players test card interactions long term.
How to use this list today
Pick S and A relics first, then fill gaps with solid B options. Adjust for your main deck, but avoid overvaluing rare cosmetic items.
A simple ranking turns relic choice from guesswork into repeatable strategy. This structure helps new and veteran players build reliable decks.
Q: Does this tier list apply to all difficulties?
Most relics stay strong, though boss fights can shift value for a few specific options.
Q: Will future patches change these ranks?
Yes, patches can move relics up or down as card pools and mechanics evolve.
